The researchers discovered that amongst 365 pregnant ladies, the check helped spot these at increased threat of preterm beginning. Overall, 73 ladies delivered prematurely, and those that’d proven altering and various vaginal microbiomes, together with irritation, had been at elevated threat.
The findings had been revealed on-line not too long ago within the journal Nature Communications.
More analysis is required earlier than the check turns into obtainable. MacIntyre stated his crew is working to enhance its efficiency, and make the testing gadget possible for “bedside” use — by miniaturizing and automating it.
What could be carried out when ladies are discovered to be at heightened threat of preterm beginning?
Currently, MacIntyre stated, two choices can be found to curb the danger: the hormone progesterone, which might delay beginning in some instances; and, in ladies with weak point within the cervix, inserting a sew to assist hold it closed.
But it is also useful to know when a lady is at heightened threat so her obstetrician can monitor her extra intently, stated Stacey Stewart, president and CEO of the March of Dimes, which helped fund the analysis.
Stewart referred to as the brand new check “an enormous step ahead” — but in addition famous that there will not be any single “silver bullet” reply to the issue of preterm beginning.
There are varied threat elements for early supply, Stewart identified. They embrace having a historical past of preterm beginning or lower than 18 months between pregnancies; well being situations like hypertension and diabetes; and way of life habits like smoking and substance abuse.
Beyond that, there are social and financial elements. Women with low incomes, lack of prenatal care, or publicity to continual stress or home abuse are at heightened threat.
In the United States, Stewart stated, ladies of colour are disproportionately affected: Almost 17% of Black infants are born preterm annually, in line with the March of Dimes.
While researchers work on exams to raised establish ladies in danger and perceive the exact causes of preterm beginning, Stewart stated ladies can take steps to help a wholesome being pregnant.
Ideally, she stated, they need to work with their well being care supplier to get any continual well being situations underneath management earlier than being pregnant. And as quickly as a lady is aware of she’s pregnant, she ought to search prenatal care.