Metabolic Syndrome Ups Odds of ARDS, Death in COVID-19

MONDAY, Jan. 3, 2022 (HealthDay News) — For hospitalized COVID-19 sufferers, the presence of metabolic syndrome is related to elevated odds of acute respiratory misery syndrome (ARDS) and mortality, in keeping with a examine revealed on-line Dec. 22 in JAMA Network Open.

Joshua L. Denson, M.D., from the Tulane University School of Medicine in New Orleans, and colleagues performed a multicenter cohort examine to look at whether or not metabolic syndrome is related to an elevated threat for ARDS and loss of life from COVID-19. Outcomes had been in contrast for sufferers hospitalized with COVID-19 with metabolic syndrome (three or extra of the next: weight problems, prediabetes or diabetes, hypertension, dyslipidemia; 5,069 adults) and controls with out metabolic syndrome (23,971 adults).

The researchers discovered that metabolic syndrome was related to an elevated threat for intensive care unit (ICU) admission, invasive mechanical air flow, ARDS, and mortality (adjusted odds ratios, 1.32, 1.45, 1.36, and 1.19, respectively) and with extended hospital and ICU size of keep (median, 8.0 versus 6.8 days and seven.0 versus 6.4 days, respectively). The threat for ARDS elevated in an additive method with every further metabolic syndrome criterion (one criterion: 10.4 %; two standards: 15.3 %; three standards: 19.3 %; 4 standards: 24.3 %).

“Given the excessive charges of metabolic syndrome, weight problems, and diabetes within the United States, one speculation for why the United States led the world in COVID-19 circumstances and deaths may very well be the excessive prevalence of metabolic syndrome on this inhabitants,” the authors write.

Several authors disclosed monetary ties to the pharmaceutical trade.